Abstract In this study, we Backpacks investigate the G2 checkpoint activated by chromosome entanglements, the so-called Decatenation Checkpoint (DC), which can be activated by TOP2A catalytic inhibition.Specifically, we focus on the spontaneous ability of cells to bypass or override this checkpoint, referred to as checkpoint adaptation.Some factors
Correct setup of the substantia nigra requires Reelin-mediated fast, laterally-directed migration of dopaminergic neurons
Midbrain dopaminergic (mDA) neurons migrate to form the laterally-located substantia nigra pars compacta (SN) and medially-located ventral tegmental 2 Layered Wooden Car Visor Clip area (VTA), but little is known about the underlying cellular and molecular processes.Here we visualize the dynamic cell morphologies of tangentially migrating SN-mDA ne
Transformative conflict mediation in multi-faith schools in South Africa
Contradictions and contestations with regard to the implementation of religion policies have become a worldwide phenomenon.Research suggest an increasing number of costly and protracted court and legislative battles between schools and parents over religion in schools.In this article, I aim to highlight some of the conflicting issues that need to t